Application

Tebbe reagent can be used:For the conversion of carbonyl groups of chlorophyll derivatives into the corresponding exo-methylene (or vinylidene) groups.In the synthesis of β-C-glycosides from 3-OH glycol esters.As a versatile methylenation reagent for the conversion of ketones and aldehydes to olefins. It offers facile reaction with hindered ketones and allows the conversion of esters to vinyl ethers.To olefinate aldehydes.To methylenate a chiral polyhydroxyketone with high diasteroselctivity.

General description

Tebbe reagent is a Lewis acid stabilized organometallic compound, which is used to transform carbonyl groups into β-substituted methylenes. It also reacts with a wide range of carbonyl compounds, including esters, amides, and lactones to yield corresponding olefins.

Legal Information

Sure/Seal is a trademark of Sigma-Aldrich Co. LLC

Packaging

25, 4×25, 100 mL in Sure/Seal™

The 25 mL Sure/Seal^™ bottle is recommended as a single-use bottle. Repeated punctures will likely result in decreased performance of product.